
Palmitoyl Hexapeptide-52
Encapsulated and delivered directly to where it's needed, helping to visibly smooth the look of expression lines and wrinkles without a single needle.
Smooth expression lines, calm redness, repair
FINE LINES & WRINKLES | STRESSED SKIN | REDNESS | DEHYDRATION | BARRIER DAMAGE
The power of five serums in one.
Powered by encapsulated, drone-delivered peptides, this multi-award-winning serum helps visibly soften lines and wrinkles, calm reactive skin and repair the skin barrier for a calmer, smoother and plumper complexion.
Clinically proven to improve skin cell repair by 42.6% in 24 hours (in vitro).*
We’re confident in our formulations and we want you to feel the same before you commit.
Give your skin 30 days with any Sachi Skincare . If you do not notice a difference, we will provide a full refund or issue full store credit via gift card. No lengthy explanations, no back-and-forth.
Smooths the look of lines and wrinkles
Provides lasting hydration for a smoother, plumper complexion
Calms visible reactivity and irritation
Restores balance to overwhelmed skin
Strengthens and supports the skin barrier
Supports skin recovery and regeneration
Suitable for post-treatment, post-retinoid skin & pregnancy safe
"Over the years, I have layered different serums, to support skin strength, smooth expression lines and promote plumpness, whilst also trying to prevent sensitivity and reactiveness my skin experiences over winter. I quickly realised how I was overloading my skin and damaging the skin barrier.
When creating Peptide Pro Resilience® Serum Concentrate, I wanted to combine several existing serums into one. I focused on antioxidants, peptides, anti-redness, repair, barrier, anti-acne and post-suncare altogether in an oil-free formulation, to boost skin resilience in one simple but incredibly intelligent step." - Farah
A lightweight, gentle yet powerful formula driven by encapsulated, drone-delivered peptides, an advanced delivery system designed to target deeper layers for enhanced efficacy and support targeted skin repair where it is needed most.
At its core, this is a multi-pathway resilience system combining a targeted peptide delivery system with a 10.5% Ayurvedic Bioflavonoid Complex, a concentrated blend of antioxidant-rich botanicals traditionally used to calm, restore and strengthen skin.
Paired with CM Beta Glucan Technology and 5 multi-molecular hydrators, it works to repair, soothe, hydrate and reinforce the skin barrier while improving resilience over time.
This integrated approach helps restore balance to sensitised, reactive or post-treatment skin, including after retinoid use, supporting recovery when your skin needs it most.
saw smoother lines and wrinkles*
felt firmer, more lifted skin*
noticed dark spots and uneven tone visibly improved*

Encapsulated and delivered directly to where it's needed, helping to visibly smooth the look of expression lines and wrinkles without a single needle.

The precision targeting peptide that works in synergy with Hexapeptide-52, together delivering a visibly smoother and firmer-looking skin.

A powerhouse humectant that attracts and locks in moisture whilst visibly supporting a calmer, more resilient-looking skin.

Together they deliver deep, lasting moisture for a visibly plumper and more supple-looking skin.

Draw moisture to the surface whilst visibly calm and soothe, helping skin look and feel more comfortable.

Powerful brighteners that work together to visibly fade the appearance of dark spots and uneven skin tone.

Known for its soothing properties, visibly calm the look of redness and irritation.

Protect the skin against UV-induced dullness and daily environmental stressors.

Visibly soothe the look of redness whilst supporting a firmer, more supple-looking skin.

The building blocks of a healthy-looking skin barrier. Help visibly restore the appearance of a smooth, resilient skin.

A naturally occurring skin-identical lipid that helps support the appearance of a balanced, healthy-looking skin.

A plant-derived skin-identical lipid that works alongside ceramides to help maintain the appearance of a smooth and well-protected skin.

A stabilised, bioavailable form of rosemary antioxidant that helps protect against environmental damage for a more resilient-looking skin.

A stabilised form of caffeic acid (a potent antioxidant) that helps visibly support a calmer, more even-looking skin tone whilst defending against environmental stressors.

A stabilised form of gallic acid delivering antioxidant support to help skin look visibly soothed and more balanced.
Encapsulated and delivered directly to where it's needed, helping to visibly smooth the look of expression lines and wrinkles without a single needle.
The precision targeting peptide that works in synergy with Hexapeptide-52, together delivering a visibly smoother and firmer-looking skin.
A powerhouse humectant that attracts and locks in moisture whilst visibly supporting a calmer, more resilient-looking skin.
Together they deliver deep, lasting moisture for a visibly plumper and more supple-looking skin.
Draw moisture to the surface whilst visibly calm and soothe, helping skin look and feel more comfortable.
Powerful brighteners that work together to visibly fade the appearance of dark spots and uneven skin tone.
Known for its soothing properties, visibly calm the look of redness and irritation.
Protect the skin against UV-induced dullness and daily environmental stressors.
Visibly soothe the look of redness whilst supporting a firmer, more supple-looking skin.
The building blocks of a healthy-looking skin barrier. Help visibly restore the appearance of a smooth, resilient skin.
A naturally occurring skin-identical lipid that helps support the appearance of a balanced, healthy-looking skin.
A plant-derived skin-identical lipid that works alongside ceramides to help maintain the appearance of a smooth and well-protected skin.
A stabilised, bioavailable form of rosemary antioxidant that helps protect against environmental damage for a more resilient-looking skin.
A stabilised form of caffeic acid (a potent antioxidant) that helps visibly support a calmer, more even-looking skin tone whilst defending against environmental stressors.
A stabilised form of gallic acid delivering antioxidant support to help skin look visibly soothed and more balanced.
Listed in descending order of concentration (INCI)
A targeted action approach to promote firmness and smooth the appearance of contraction lines. Peptides help firm and smooth skin, but only if they reach the right cells. Acting as intelligent carriers, our microscopic “drones” safeguard the actives in the serum as they travel through the skin before releasing them exactly where they can perform at their highest potential. This advanced targeting technology enhances peptide stability and bioavailability, allowing the formula to deliver visible firming and reparative benefits with exceptional efficiency and minimal irritation.
Advanced formulas created for focused routines; transformative results, fewer steps.
The perfect cleanse to promote great skin health and optimum results.
A serum to target your key skincare concerns.
An overnight treatment to help you achieve your highest skin goals while you sleep.
A powerful, multi-tasking moisturiser to complement your routine and lock in hydration.
MY RITUAL
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Firm, lift, reduce multiple signs of ageing
Smooth expression lines, calm redness, repair
"The serum is exactly what was missing from the barrier repair products currently available. It's an elegant lightweight formula that visibly calms the skin and restores plumpness. Results over buzzwords with this one!"
Dr Piotr Janicki, Dermatologist
@skinunmasked
"I've been loving it! I've been using it daily in my AM routine. The texture is just beautiful and it's so hydrating. My skin is definitely more calm and less red."
Fiona, Skincare Influencer
@fionas50life
"I've been using the Pro Resilience® Serum for a few weeks now and have fallen in love with it! It works perfectly alongside the Triphala Pigmentation Corrector and leaves my skin feeling intensely hydrated, looking calm and all round happy. I can’t imagine not having it in my routine now."
Lauren, Skincare Influencer
@themakeupmaestro
Within 24 hrs: Skin instantly feels hydrated, plumper and calm.
Within 1-2 weeks: Skin will feel more hydrated; post-sun skin will feel calmer, and reactive skin conditions will feel soothed. Skin will look healthier and more radiant.
Within 2-8 weeks: Skin will feel less reactive, and texture will appear smoother and visibly more balanced.
Within 12 weeks+: Over time, the powerful fusion of antioxidants and peptides will continue to support skin firmness, elasticity, collagen and repair, helping to reduce the appearance of fine lines and wrinkles.
The Peptide Pro Resilience® Serum Concentrate was developed to combine several steps into one, saving you time and money. We know that the variety of serum options can become overwhelming. This multi-tasking, award-winning formula aims to address a host of skin concerns in just one bottle.
Peptide Pro Resilience® Serum Concentrate can help with reddened and post blemish skins to support skin recovery and repair, thanks to Arnica Extract, which can help to support skin capillary and strength. Please note, PIE is a vascular skin concern and can take some time to resolve. We suggest pairing Peptide Pro Resilience® Serum Concentrate with Triphala Pigmentation Corrector for optimum results.
Rosacea is a medical skin condition and we always recommend that you speak with your doctor first. However, Peptide Pro Resilience® Serum Concentrate can help to relieve some of the symptoms and redness associated with rosacea, for visibly calmer and more even skin.
While Peptide Pro Resilience® doesn’t directly alter GLP-1 pathways, it does address many of the visible skin changes associated with GLP-. It's peptide complex, CM-β-glucan, and dermal-strengthening actives support collagen integrity, improve firmness, boost resilience, and enhance the skin’s ability to repair helping counter the tired, slack, or quickly “deflated” look some experience on GLP-1 medications.
Yes! The serum is safe to use, but always consult your doctor for personal advice if concerned.
A luxurious, lightweight fluid emulsion. It has no artificial fragrance.